Can i use the Visual Studio 2010 to programming in SalesLogix Web 7.5?
I know people using vs2010 without problems.
You just have to make sure, that you are using the correct .net framework version.
But there is no issue opening the slx web site and developing for that site.
Alexander is right. Just be sure to choose .net 3.5 when you create your dll or other component and you should be set.